Finally, we also comment on the effect that aggravating conditions, such as oxidative stress and aging, have on the functioning of the autophagic system and its ability to cope with altered proteins. 最后,我们同样评论加重情况的影响,比如氧化应激和老化,自噬系统的功能和它的处理异常蛋白质的能力。
Reducing the amount of dietary fat may improve memory and help reduce the negative effects of stress and aging on thinking and learning, recent studies suggest. 最近研究资料已证明,减少脂肪摄入量,有助于改善人的记忆,减少人们因生活压力和年龄因素造成思考障碍、学习困难的不利影响。
Application of Improved Blind Hole Method to Welded Iron Tower Joint for Stress Relieving with Heat Aging 改进型盲孔法在铁塔焊接接头热时效消除应力中的应用
The past decade has witnessed a remarkable increase in our understanding of the molecular and biochemical mechanisms that determine cell survival and cell death with stress, pathology and aging. 近十年来我们对应激、病理和年龄因素在决定细胞生存和死亡的分子和生化机制方面有了明显深入的了解和认识。
The Society for Neuroscience addresses the study of brain development, sensation and perception, learning and memory, movement, sleep, stress, aging and neurological and psychiatric disorders. 神经系统科学学会:从事于脑部发育、感知、学习与记忆、运动、睡眠、压力、衰老,以及神经学和精神病学上的疾病的研究。
Effects of purslane herb on stress ability of aging mice induced by D-galactose 马齿苋对D-半乳糖衰老模型小鼠应激能力的影响
This paper discussed the free radical theory of aging, the glycation theory of aging and directed to the carbonyl stress theory of aging, which was implied from the biochemistry of age pigment formation. 本文讨论了衰老的自由基学说、糖基化学说以及在其基础上根据老年色素的形成机制发展而成的羰基毒化衰老学说。
Conclusion: Proper swim stress may delay aging process by improving the aging mice ′ behavior and immune function. 结论:适宜游泳应激可改善衰老小鼠行为表现和免疫功能以延缓衰老进程。
In order to reduce the casting residual stress, a new aging method, static force method was introduced. 为了消除铸件残余应力,本文提出一种新的时效方法&静态作用应力法。
Strength Degradation and Recovery of Silica based Optical Fiber under the Zero stress Aging Condition 无应力老化条件下二氧化硅基玻璃光纤强度衰退和复原
It is necessary to conduct the accelerated multi stress aging test on motor stator bar specimen in order to explore its aging law, assess its remaining life and find a set of characteristic parameters which can indicate the condition of the insulation. 为了研究主绝缘老化机理,评估其剩余寿命,需要对电动机定子线棒进行多因子应力综合老化试验,并寻找能反映主绝缘老化程度的特征参量。
Based on the carbonyl stress theory of aging, we designed preventions or interventions that specifically target each step of carbonyl stress. 基于羰基毒化衰老学说,我们分析了从各个阶段来预防及干预体内的羰基毒化。
Based on the carbonyl stress hypothesis of aging, a variety of reactive carbonyl intermediates, the common products of the Maillard reactions and advanced lipid peroxidation reactions, can affect the oxidative modification of tissue proteins directly. 基于羰基毒害衰老理论,具有强烈反应活性的羰基类化合物是非酶糖基化和脂质过氧化的共同中间产物,它们是造成蛋白修饰的直接原因之一。
Carbonyl Stress in Aging Process 衰老过程中的羰基应激
After reviewed the carbonyl stress in aging biochemistry, this paper turn to develop the detection method of age pigments and study the mechanism of meltonin's antiaging function. 本文综述了衰老生化中的羰基毒害,并致力于改进老年色素测定方法和美拉托林抗羰基毒害机理的初探。
According to this model, there is a critical time during stress aging, at which a maximum level of grain boundary segregation/ dilution is occurred. 根据此模型,应力时效过程中存在一个临界时间,在此时间,应力引起的晶界偏聚或贫化程度将达到一个极大值。
Effect of tea polyphenols on the mitochondria respiratory function and level of oxygen stress in aging rat 老年大鼠线粒体呼吸功能及氧应激水平与茶多酚
According to carbonyl stress theory of aging, carbonyl-amine reaction as a common reaction of free radical oxidation and non-enzymatic glycosylation is an inevitable and irreversible core process during the slow aging procedure caused by oxidation and glycosylation. 羰基毒害衰老学说指出,羰-氨反应作为自由基氧化和非酶糖基化两大生化反应的兼有反应,是氧化和糖基化造成缓慢生物老化过程的不可避免且大部分不可修复的核心过程。
The result indicates that 20 mg/ kg EMP can increase the activity of anti-oxidation enzyme, improve free radical metabolism and protect ultrastructure of myocardium from oxidative stress in aging mice. 这表明20mg/kg的EMP具有增强衰老小鼠心肌抗氧化酶活性,改善心肌自由基代谢,保护心肌细胞超微结构的作用。
Objective This study was to compare the effects of chronic experimental stress and aging on insulin sensitivity at insulin receptor of liver plasma membranes and its autophosphorylation in the aged mice compared with those in the young and the adult diabetes-susceptible mice. 目的研究慢性应激和增龄对小剂量链脲佐菌素诱导的糖尿病易感小鼠胰岛素敏感性的影响,并从胰岛素受体水平探讨其机理。
Both nucleation and growth are affected by the external stress by two-step aging simulation, but the effect degree depends on lattice misfit. 采用双级时效模拟方式时,外加应力场对析出相的成核及生长阶段均有影响,只是影响程度与析出相自身的点阵错配度有关。
TEM microstructure showed that stress aging eliminate PFZ and inhibited GBP which was due to the non-equilibrium grain boundary segregation of solutes. 组织观察表明应力时效消除了PFZ,抑制了晶界析出相,是溶质在压应力下发生晶界非平衡偏聚所致。
Study on the initial elastic modulus, the stress-strain curves and the distribution curve of interface maximum shear stress changing with aging time of the cord-rubber with different loadings were carried out. 研究了各种载荷条件下帘线-橡胶的初始弹性模量和应力-应变曲线随老化时间的变化,并得到了老化前后帘线-橡胶界面最大剪应力分布。
However, in abnormal conditions, such as oxidative stress, ischemia and aging can disturb the balance of mitochondrial fusion and fission. 异常情况,如氧化应激、缺血、老龄化等病理环境则会导致线粒体融合、分裂失衡。
These results further confirm the roles of phospholipase and the changes of phospholipids in abiotic stress and aging. 这些发现,促进了我们对植物磷脂酶和磷脂变化在植物逆境和衰老中作用的了解。
Chronic adverse stress and aging both can do harm to animals 'cognitive function and both of them have synergistic action. And chronic stress can accelerate the process of aging. 3. 慢性不良应激刺激及衰老对动物的认知功能都有损害作用,二者有协同作用,而且慢性应激刺激可加速衰老的过程。